Researchers from Lleida publish a study on the differences between patients with MPOC due to the fact that they are male or female
The article, published in the journal BMC Pulmonary Medicine, determines that men and women have similar comorbidities, but women turn out to be more susceptible to the harmful effects of tobacco and have more bronchiectasis, among other effects.
The doctors from Lleida Josep Montserrat, head of studies at the MAFiC Lleida Teaching Unit; Maite Castañ, doctor at the HEAD OF Eixample; Marta Ortega, coordinator of the USR Lleida-ICS and researcher at IDIAP Jordi Gol; Miquel Alsedà, epidemiologist and researcher at IRBLleida; Ferran Barbé, head of the Pneumology service at HUAV; Josep Ramon Marsal, researcher at the Valle de Hebrón Cardiovascular Epidemiology Unit, and Pere Godoy, head of the Public Health Epidemiological Surveillance Service and IRBLleida researcher, have published the study 'Clinico-epidemiological characteristics of men and women with a new diagnosis of Chronic Obstructive Pulmonary Disease: a database (SIDIAP) study 'in the scientific journal BMC Pulmonary Medicine.
The study is the result of the SIDIAP grant (IDIAP Jordi Gol) won by the Research Group in 2017 and which allows access to variables registered to the eCAP of more than 5.5 million users of ICS Primary Care. In this case, the researchers wanted to determine if there were clinical-epidemiological differences, associated comorbidities, and analytical and biomedical parameters among the patients diagnosed with Primary MPOC due to the fact that they were male or female.
A cross-sectional study was designed based on the bigdata (SIDIAP) during the period between January 2012 and December 2017. The eCAP variables of 5,800,000 users from a total of 279 Primary Care Centers throughout Catalonia were reviewed and those variables of interest were collected from among the users who met the inclusion criteria (see tables 1 and 2 of the article by clicking the link at the end of this newsletter).
Of an initial sample of 800,000 people, only 3% were patients diagnosed with MPOC, of which 22.9% were women. The risk factors most frequently associated with women were bronchiectasis (Ora = 20.5), age over 71 years (Ora = 18.8), chorus pulmonale (Ora = 5.2) and lung cancer (Ora = 3.6). The study determined that men and women share similar comorbidities (smoking, alcohol consumption, lung cancer, bronchiectasis, chorus pulmonale, obstructive sleep apnea syndrome (OSAS), ischemic heart disease, osteoporosis, depressive sd, hypertension, DM2, disease chronic kidney disease, anemia, atrial fibrillation). Instead, they differ in that the strength of association is different in each of the two groups. In this case, women turn out to be more susceptible to the harmful effects of tobacco and present, at the same time, a higher proportion of bronchiectasis and OSAS.
Knowing the distribution and the strength of association of each comorbidity and risk factor in men and women diagnosed with MPOC allows to have additional information to daily clinical practice when identifying those patients with the highest suspicion of suffering from MPOC.
In this link you can access the full article.
