Almost 80% of patients with type 2 diabetes should have personalized treatment
This is indicated by a study published in Primary Care Diabetes directed by Manel Mata, researcher at IDIAP Jordi Gol and CIBERDEM and by Dídac Mauricio, leader of the Endocrinology, Diabetes and Nutrition research group at the Sant Pau Biomedical Research Institute.
The majority of patients with type 2 diabetes mellitus (almost 80%) meet one of the five clinical conditions that must be taken into account to individualize their treatment: an age greater than 75 years, obesity, chronic kidney or cardiovascular disease, and heart failure .
Researchers have described the characteristics and antidiabetic treatment in a database of 373,185 patients with type 2 diabetes, and of these, the five most relevant clinical conditions have been determined when proposing a treatment. The team observed that 37% were over 75 years old, 45% obese, 33% chronic kidney disease, 23.2% cardiovascular disease, and 6.9% heart failure, according to the clinical conditions prioritized in the therapeutic algorithm. Spanish of the GDPS Network (Network of Study Groups on Diabetes in Primary Care).
Insulin was prescribed more frequently in patients with chronic kidney disease, cardiovascular disease, and heart failure, while GLP-1 receptor agonists or sodium-glucose cotransporter type 2 (iSGLT2) inhibitors are prescribed much less than those prescribed. suggested by clinical practice guidelines. Among patients with severe renal failure, contraindicated drugs such as metformin (16%) and sulfonylureas (6.1%) are still used. According to the KDIGO renal risk categories, it was moderate to very high in 40% of patients.
According to the Manel Mata researcher, “it is important to note that the majority of people with type 2 diabetes meet one of the five clinical conditions that must be considered for the individualization of treatment, and it is important to note that a large number of patients with severe renal insufficiency who used contraindicated drugs ”.
