The SensiTEbre group focuses its research on improving the approach to Fibromyalgia and Chronic Fatigue from Primary Care, being highly practical and implementable, with a significant social impact. It investigates using mixed methodology, including citizen and healthcare professional involvement, to optimize the effectiveness of interventions and therapeutic adherence. The group has three research lines: (1) Research line in “Epidemiology” and biopsychosocial factors associated with Fibromyalgia and other chronic and mental illnesses (BiSocial Line); (2) Research line in multidisciplinary interventions to improve Fibromyalgia and Chronic Fatigue (InterBÉ Line), with three sub-lines, Multidisciplinary Interventions in Fibromyalgia, Physio-pedagogy, and pain neuroscience, Cognitive-behavioral therapy in Fibromyalgia and Chronic Fatigue; (3) Research line in “Nutrition, Chronobiology, and Exercise” in Fibromyalgia and Chronic Fatigue (SYNC Line).