GROICAP

Responsable del grupo
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Marta Zwart Salmerón,
mzwart.girona.ics@gencat.cat
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Publicaciones

Rurality and COVID-19 Outcomes: Unraveling the Impact of Nursing Home Residency Using Bayesian Analysis

J. MARTÍNEZ-REDONDO, M. PONS, A. LLEVADOT, J. SALUD and C. COMAS
Journal of Clinical Medicine. 2024 Dec 1; . doi:10.3390/jcm13237244; PMID:39685704

  • Ans: 01/12/2024
  • FI: 3

Background and Objectives: Many studies have analyzed the impact of rurality on the incidence and consequences of COVID-19 infection. However, these studies have not considered the impact of different numbers of nursing homes in rural, semi-urban, or urban areas. Our objective was to analyze the effect of the factor of rurality on the incidence and mortality of COVID-19 while accounting for the impact of the variable of nursing home residency. In addition, we performed a comparative analysis of the infected population in semi-urban and rural areas. Methods: We first analyzed COVID-19 infection in all populations in the Balaguer Primary Health Care Area before examining the impact of rurality using Bayesian logistic regression analysis, specifically excluding the population living in nursing homes. We also performed an epidemiological and clinical analysis comparing rural and semi-urban areas. Results: We found higher incidence of and higher relative and absolute mortality from COVID-19 infection in semi-urban areas than in rural areas. After excluding nursing home residents from our sample, the Bayesian analysis indicated that rurality was not protective against COVID-19 infection or mortality. The incidence rates, specific mortality rates, and case fatality rates were similar in semi-urban and rural areas. All comorbidities, except chronic obstructive pulmonary disease, were associated with higher mortality, while no symptoms were associated with higher mortality. Conclusions: Excluding the population residing in nursing homes from the analysis, we found that rurality was not a protective factor against either infection or mortality during the first COVID-19 wave. Our Bayesian model analysis confirmed that rurality alone did not enhance survival among residents of rural areas.

Population Older than 69 Had Similar Fatality Rates Independently If They Were Admitted in Nursing Homes or Lived in the Community: A Retrospective Observational Study during COVID-19 First Wave.

Martínez-Redondo J, Comas C, García-Serrano C, Crespo-Pons M, Biendicho Palau P, Vila Parrot T, Reventoz Martínez F, Aran Solé L, Arola Serra N, Tarragona Tassies E and Pujol Salud J
Geriatrics. 2023 Apr 28; . doi:10.3390/geriatrics8030048; PMID:37218828

  • Ans: 28/04/2023
  • FI:

The aim of this study is to assess the influence of living in nursing homes on COVID-19-related mortality, and to calculate the real specific mortality rate caused by COVID-19 among people older than 20 years of age in the Balaguer Primary Care Centre Health Area during the first wave of the pandemic. We conducted an observational study based on a database generated between March and May 2020, analysing COVID-19-related mortality as a dependent variable, and including different independent variables, such as living in a nursing home or in the community (outside nursing homes), age, sex, symptoms, pre-existing conditions, and hospital admission. To evaluate the associations between the independent variables and mortality, we calculated the absolute and relative frequencies, and performed a chi-square test. To avoid the impact of the age variable on mortality and to assess the influence of the «living in a nursing home» variable, we established comparisons between infected population groups over 69 years of age (in nursing homes and outside nursing homes). Living in a nursing home was associated with a higher incidence of COVID-19 infection, but not with higher mortality in patients over 69 years of age (p = 0.614). The real specific mortality rate caused by COVID-19 was 2.27(0)/(00). In the study of the entire sample, all the comorbidities studied were associated with higher mortality; however, the comorbidities were not associated with higher mortality in the infected nursing home patients group, nor in the infected community patients over 69 years of age group (except for neoplasm history in this last group). Finally, hospital admission was not associated with lower mortality in nursing home patients, nor in community patients over 69 years of age.

Enhancing Night and Day Circadian Contrast through Sleep Education in Prediabetes and Type 2 Diabetes Mellitus: A Randomized Controlled Trial

C. GARCIA-SERRANO, J. SALUD, L. ARAN-SOLE, J. SOL, S. ORTIZ-CONGOST, E. ARTIGUES-BARBERA and M. ORTEGA-BRAVO
Biology-Basel. 2022 Jun 1; . doi:10.3390/biology11060893; PMID:35741413

  • Ans: 01/06/2022
  • FI: 4.2

Simple Summary Since several studies have described a relationship between sleep disturbances and abnormal glucose metabolism, improving sleeping habits in people with type 2 diabetes should improve glucose metabolism. To prove this hypothesis, we conducted an educational intervention to ameliorate sleep hygiene through nine simple recommendations in patients with prediabetes and type 2 diabetes. We then evaluated if sleep quality, levels of blood glucose and glycated haemoglobin had improved. In the intervention group, we found a significant improvement in sleep quality and diabetes control compared with the control group. Education in sleep hygiene is an important tool for improving health in people with prediabetes and diabetes. Background: Evidence supports a causal relationship between circadian disturbance and impaired glucose homeostasis. Methods: To determine the effect of an educational intervention delivered by primary care nurses to improve sleep hygiene, a parallel, open-label clinical trial in subjects aged 18 and older with impaired fasting glucose (IFG) or type 2 diabetes mellitus (T2DM) was performed. Study variables were sex, age, fasting glucose, glycated haemoglobin A1c (HbA1c), Pittsburgh Sleep Quality Index (PSQI), sleep duration and efficiency, body mass index, antidiabetic treatment, diet and physical exercise. An individual informative educational intervention was carried out following a bidirectional feedback method. The intervention aimed to develop skills to improve sleep through nine simple tips. An analysis of covariance was performed on all the mean centred outcome variables controlling for the respective baseline scores. Results: In the intervention group, PSQI dropped, the duration and quality of sleep increased, and a decrease in fasting glucose and in HbA1c levels was observed. Conclusion: The proposed intervention is effective for improving sleep quality, length and efficiency, and for decreasing fasting glucose and HbA1c levels in only 3 months. These findings support the importance of sleep and circadian rhythm education focused on improving IFG and T2DM.

Effect of bisphosphonate withdrawal: Follow-up of a cohort of patients

C. URGELL, J. VICENTE, R. FERNANDEZ, G. BLANCO, C. NAVAJAS, A. SISO, J. MERINO and R. LEDESMA
BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY. 2022 May 1;

  • Ans: 01/05/2022
  • FI: 3.1
Percutaneous gastrostomy as a procedure to improve the survival of patients with amyotrophic lateral sclerosis

E. CASTRO-RODRIGUEZ, R. AZAGRA, X. GOMEZ-BATISTE and M. POVEDANO
ATENCION PRIMARIA. 2022 May 1; . doi:10.1016/j.aprim.2022.102322; PMID:35325790

  • Ans: 01/05/2022
  • FI: 2.5