Research Area: Mental Health

Description

Multidisciplinary group composed of 14 researchers, six general practitioners (3 of them are also doctors in medicine), a nurse practitioner, three doctors in psychology, two doctors in pharmacy, two pharmacy graduates and a doctor in psychiatry. The group originated in 1999 under the name GRAPISAM Group (Research Group in Primary Care and Mental Health) with the development of the DAPGA study that was carried out in the Mental Health Center of Gavà and the ABS Bartolomé Fabrés Anglada of Gavà. As a result of that first collaboration, others emerged, such as the ETAPS, FIBROQOL and PRODEFAR studies, which focused mainly on the evaluation of interventions aimed at the management of mental illnesses in primary care, always with a focus on health economics. In recent years, the group has grown, becoming more multidisciplinary, expanding the focus of research and increasingly specializing in the economic evaluation of health in primary care, including the evaluation of the economic impact of diseases (eg COSTDEP), the cost-effectiveness of preventive interventions (eg PREDICTD-CCRT), the cost-effectiveness of pharmacological treatments (eg INFAP) and non-pharmacological treatments (eg EUDAIMON), the cost of non-adherence and the impact of the introduction of health policies (eg NO-Iniciadores), etc. In addition, although the study of mental illnesses is still one of the main focuses of the group, the research has been extended to other pathologies, such as the management of chronic pain and fibromyalgia (eg Fibromyalgia subtypes and EUDAIMON) or multi-risk prevention (eg Econ-EIRA3). The group complements the use of clinical trials and economic evaluations with other study designs that allow it to better understand the difficulties of managing pathologies in primary care and the efficiency of treatments, such as psychometric analysis (WHODAS 2.0, CERQ, FFMQ, MISCI, etc.), qualitative research (eg, PREDICT-EVAL), systematic reviews (eg EIRA2), and epidemiological studies based on the secondary exploitation of large databases, such as SIDIAP, all within the framework of research in the field of primary care. This evolution has given way to the Research Group on Health Economics in Primary Care (ECONSAP). The main objectives of the group are to improve the quality and efficiency of mental pathologies and chronic physical diseases’ care in Primary Care - including prevention and pharmacological and non-pharmacological treatment -, to assess the cost of diseases and patients’ behavior and to develop innovative and multidisciplinary interventions in the area of Primary Care from a multidisciplinary point of view.

Research Lines

Evaluation of the cost of diseases, the efficiency of preventive interventions, the pharmacological and non-pharmacological treatment of mental illnesses and chronic physical diseases in Primary Care.

Members

Projects

The group participates in the following projects:

PI: Luciano Devis, Juan Vicente. Cost-effectiveness of a Mindfulness-Based Stress Reduction (MBSR) treatment for fibromyalgia syndrome: A 12-month randomised, controlled trial. Funding: Instituto de Salud Carlos III. Duration: 2015 - 2020

PI: Rubio Valera, Maria. Intervención del farmacéutico en el abordaje de la cesación tabáquica. Proyecto CESAR. Funding: Sociedad Española de Farmacia Familiar y Comunitarias (SEFAC). Duration: 2017 - 2019

PI: Moreno Peral, Patricia. Impacto de las Habilidades de Comunicación de Los Médicos de Familia en la Prevención de la Depresión en Atención Primaria: Cohorte Prospectiva Anidada en Un Ensayo Clínico Controlado. el Estudio Predictd- Communication. Funding: Junta de Andalucia. Duration: 2017 - 2018

PI: Feliu Soler, Albert. Prediction of treatment response and effects of Mindfulness-Based Stress Resuction program on inflammatory markers in patients with fibromyalgia: a randomized clinical trial. Funding: Fund. privada per a la recerca i la Docència Sant Joan de Déu. Duration: 2017 - 2018

PI: Luciano Devis, Juan Vicente. Impacto de un programa de Reducción del Estrés Basado en Mindfulness (MBSR) sobre marcadores inflamatorios: Ensayo clínico controlado y aleatorizado en pacientes con fibromialgia. Funding: Instituto Esmindfulness SL. Duration: 2017 - 2018

PI: Bellon Saameño, Juan Angel. Prevención de la depresión mediante una intervención personalizada basada en algoritmos predictivos y DSS utilizados por el propio paciente y su médico de familia (e-predictD). Funding: Junta de Andalucia. Duration: 2016 - 2018

PI: Serrano Blanco, Antoni. Evaluación económica de una intervención compleja multiriesgo para promover conductas saludables en personas de 45-75 años atendidas en Atención Primaria: estudio Econ-EIRA3. Funding: Instituto de Salud Carlos III. Duration: 2016 - 2018

PI: Luciano Devis, Juan Vicente. Efectos neurobiológicos de una intervención basada en mindfulness (MBSR) vs. Psico-educativa (FibroQol) en pacientes con fibromialgia (Proyecto EUDAIMON). Funding: Instituto de Salud Carlos III. Duration: 2016 - 2018

PI: Serrano Blanco, Antoni. Diagnosi de la situació de la salut mental de la població infanto-juvenil a la ciutat de Terrassa. Funding: Diputacio de Barcelona. Duration: 2017

PI: Serrano Blanco, Antoni. Diagnosi de la situació de la salut mental a la comarca d'Alt Penedès. Funding: Diputacio de Barcelona. Duration: 2017

PI: Bellon Saameño, Juan Angel. Prevención de la depresión mediante una intervención personalizada basada en algoritmos predictivos y DSS utilizados por el propio paciente y su médico de familia (e-predictD). Funding: Instituto de Salud Carlos III. Duration: 2015 - 2017

PI: Rubio Valera, Maria. El problema de la no-iniciación del tratamiento farmacológico: evaluación con métodos mixtos. Funding: Instituto de Salud Carlos III. Duration: 2015 - 2017

PI: Serrano Blanco, Antonio. Mental Health Training Through Research Network In Europe (MARATONE). Funding: European Commission. Duration: 2013 - 2017

Publications

Group Publications:

Aznar-Lou I, Fernández A, Gil-Girbau M, Fajó-Pascual M, Moreno-Peral P, Peñarrubia-María MT, Serrano-Blanco A, Sánchez-Niubó A, March-Pujol MA, Jové AM, Rubio-Valera M. Initial medication non-adherence: prevalence and predictive factors in a cohort of 1.6 million primary care patients. Br J Clin Pharmacol. 2017

Jun;83(6):1328-1340. doi: 10.1111/bcp.13215. Epub 2017 Feb 24. PubMed PMID: 28229476; PubMed Central PMCID: PMC5427227. IF: 3,493.

Berenguera A, Pons-Vigués M, Moreno-Peral P, March S, Ripoll J, Rubio-Valera M, Pombo-Ramos H, Asensio-Martínez A, Bolaños E, Martínez-Carazo C, Maderuelo-Fernández J, Martinez-Andrés M, Pujol-Ribera E. Beyond the consultation room: Proposals to approach health promotion in primary care according to health-care users, key community informants and primary care centre workers. Health Expect. 2017;20(5):896-910. PMID:28116774. IF: 1,669.

Cebolla A, Campos D, Galiana L, Oliver A, Tomás JM, Feliu-Soler A, Soler J, García-Campayo J, Demarzo M, Baños RM. Exploring relations among mindfulness facets and various meditation practices: Do they work in different ways?. Consciousness and cognition. 2017 Mar; 49:172-180. doi:10.1016/j.concog.2017.01.012. Epub 2017 Feb 20. PMID:28214767. IF: 2,144.

Cuevas-Esteban J, Iglesias-González M, Rubio-Valera M, Serra-Mestres J, Serrano-Blanco A, Baladon L. Prevalence and characteristics of catatonia on admission to an acute geriatric psychiatry ward. Progress in neuro-psychopharmacology & biological psychiatry. 2017 May; 78:27-33. doi:10.1016/j.pnpbp.2017.05.013. Epub 2017 May 19. PMID:28533149. IF: 4,187.

Domènech-Abella J, Lara E, Rubio-Valera M, Olaya B, Moneta MV, Rico-Uribe LA, Ayuso-Mateos JL, Mundó J, Haro JM. Loneliness and depression in the elderly: the role of social network. Social psychiatry and psychiatric epidemiology. 2017 Apr; 52(4):381-390. doi:10.1007/s00127-017-1339-3. Epub 2017 Feb 02. PMID:28154893. IF: 2,922.

Luciano JV, D'Amico F, Feliu-Soler A, McCracken LM, Aguado J, Peñarrubia-María MT, Knapp M, Serrano-Blanco A, García-Campayo J. Cost-Utility of Group Acceptance and Commitment Therapy for Fibromyalgia Versus Recommended Drugs: An Economic Analysis Alongside a 6-Month Randomized Controlled Trial Conducted in Spain (EFFIGACT Study). J Pain. 2017 Jul;18(7):868-880. doi: 10.1016/j.jpain.2017.03.001. Epub 2017 Mar 23. PubMed PMID: 28342891. IF: 4,519.

Resurrección DM, Motrico E, Rigabert A, Rubio-Valera M, Conejo-Cerón S, Pastor L, Moreno-Peral P. Barriers for Nonparticipation and Dropout of Women in Cardiac Rehabilitation Programs: A Systematic Review. J Womens Health (Larchmt). 2017 Aug;26(8):849-859. doi: 10.1089/jwh.2016.6249. Epub 2017 Apr 7. Review. PubMed PMID: 28388314. IF: 2,322.

Romero-Sanchiz P, Nogueira-Arjona R, García-Ruiz A, Luciano JV, García Campayo J, Gili M, Botella C, Baños R, Castro A, López-Del-Hoyo Y, Pérez Ara MÁ, Modrego-Alarcón M, Mayoral Cleríes F. Economic evaluation of a guided and unguided internet-based CBT intervention for major depression: Results from a multi-center, three-armed randomized controlled trial conducted in primary care. PloS one. 2017 ; 12(2):e0172741. doi:10.1371/journal.pone.0172741. Epub 2017 Feb 27. pmc:PMC5328395. PMID:28241025. IF: 2,806.

The group participates in the following publications:

Andrés-Rodríguez L, Pérez-Aranda A, Feliu-Soler A, Rubio-Valera M, Aznar-Lou I, Serrano-Blanco A, Juncosa M, Tosas A, Bernadàs A, Luciano JV. Effectiveness of the "What's Up!" Intervention to Reduce Stigma and Psychometric Properties of the Youth Program Questionnaire (YPQ): Results from a Cluster Non-randomized Controlled Trial Conducted in Catalan High Schools. Front Psychol. 2017;14:8-1608. PMID:28959228. IF: 2,323.

Aznar-Lou I, Fernández A, Gil-Girbau M, Sabés-Figuera R, Fajó-Pascual M, Peñarrubia-María MT, Serrano-Blanco A, Moreno-Peral P, Sánchez-Niubó A, March-Pujol M, Rubio-Valera M. Impact of initial medication non-adherence on use of healthcare services and sick leave: a longitudinal study in a large primary care cohort in Spain. The British journal of general practice : the journal of the Royal College of General Practitioners. 2017 Sep; 67(662):e614-e622. doi:10.3399/bjgp17X692129. Epub 2017 Jul 31. pmc:PMC5569741. PMID:28760740. IF: 2,760.

Baladon L, Rubio M. Multidimensional determinants of the caregiving burden among Chinese male caregivers of older family members in Hong Kong. Aging Ment Health. 2017;25:1-10. PMID:28541777. IF: 2,658.

Elices M, Soler J, Feliu-Soler A, Carmona C, Tiana T, Pascual JC, García-Palacios A, Álvarez E. Combining emotion regulation and mindfulness skills for preventing depression relapse: a randomized-controlled study. Borderline Personal Disord Emot Dysregul. 2017 Jul 5;4:13. doi: 10.1186/s40479-017-0064-6. eCollection 2017. PubMed PMID: 28690851; PubMed Central PMCID: PMC5497384.

Federici S, Bracalenti M, Meloni F, Luciano JV. World Health Organization disability assessment schedule 2.0: An international systematic review. Disability and rehabilitation. 2017 Nov; 39(23):2347-2380. doi:10.1080/09638288.2016.1223177. Epub 2016 Nov 07. PMID:27820966. IF: 1,804.

Feliu A, Pérez A, Andrés L, Peñarrubia MT, Garcia J, Bellon JA, Luciano JV. Psychometric Properties of the Cognitive Emotion Regulation Questionnaire (CERQ) in Patients with Fibromyalgia Syndrome. Front Psychol. 2017;8:2075-2075. PMID:29321750. IF: 2,323.

Fernandez A, Gillespie JA, Smith-Merry J, Feng X, Astell-Burt T, Maas C, Salvador-Carulla L. Integrated mental health atlas of the Western Sydney Local Health District: gaps and recommendations. Australian health review: a publication of the Australian Hospital Association. 2017 Mar; 41(1):38-44. doi:10.1071/AH15154. PMID:27007640. IF: 1,343.

Iglesias-González M, Aznar-Lou I, Gil-Girbau M, Moreno-Peral P, Peñarrubia-María MT, Rubio-Valera M, Serrano-Blanco A. Comparing watchful waiting with antidepressants for the management of subclinical depression symptoms to mild-moderate depression in primary care: a systematic review. Fam Pract. 2017 Nov 16;34(6):639-648. doi: 10.1093/fampra/cmx054. PubMed PMID: 28985309. IF: 1,804.

Moreno-Peral P, Conejo-Cerón S, Rubio-Valera M, Fernández A, Navas-Campaña D, Rodríguez-Morejón A, Motrico E, Rigabert A, Luna JD, Martín-Pérez C, Rodríguez-Bayón A, Ballesta-Rodríguez M, Luciano JV, Bellón JÁ Effectiveness of Psychological and/or Educational Interventions in the Prevention of Anxiety: A Systematic Review, Meta-analysis, and Meta-regression. JAMA psychiatry. 2017;74(10):1021-1029. PMID:28877316. IF: 15,307.

Mugica F, Nebot À, Bagherpour S, Baladón L, Serrano-Blanco A. A model for continuous monitoring of patients with major depression in short and long term periods. Technology and health care : official journal of the European Society for Engineering and Medicine. 2017; 25(3):487-511. doi:10.3233/THC-161289. PMID:28009344. IF: 0,724.

Serrano-Blanco A, Rubio-Valera M, Aznar-Lou I, Baladón Higuera L, Gibert K, Gracia Canales A, Kaskens L, Ortiz JM, Salvador-Carulla L. In-patient costs of agitation and containment in a mental health catchment area. BMC Psychiatry. 2017 Jun 6;17(1):212. doi: 10.1186/s12888-017-1373-4. PubMed PMID: 28583103; PubMed Central PMCID: PMC5460463. IF: 2,613.

Awards

Fundación mutual médica. Accesit Dr. Font Award. Intervention to Prevent Major Depression in Primary Care. Bellon J, Conejo S, Moreno P, King M, Nazareth I, Martín C, Fernández C, Rodríguez A, Fernández A, Aiarzaguena J, Montón C, Rodriguez E, Ballesta M, Serrano A, Lafuente M, Muñoz M, Araujo L, Palao D, Bully P, Navas D, Mendive J, Aranda J, Rodríguez A, Salvador L, Luna J.

Best paper AES (Asociación Economía de la Salud) 2017. British Journal of General Practice. Impact of initial medication non-adherence on use of healthcare services and sick leave: a longitudinal study in a large primary care cohort in Spain. Aznar I, Fernández A, Gil MM, Peñarrubia MT, Serrano A, Moreno P, March M, Rubio M.

Indicators